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Research Use Only · Reference compounds for in-vitro laboratory study · Not for human or animal consumption

La Catégorie

Growth & Performance

GHRH analogs and growth-hormone-axis reference compounds studied in laboratory models of pituitary signaling and IGF-1 expression.

Reference Notes

Two inputs to one output

Pituitary somatotrophs receive two distinct stimulatory signals. GHRH analogs act on the GHRH receptor; growth-hormone secretagogues act on the ghrelin receptor, GHS-R1a. Both converge on pulsatile growth-hormone release, which in turn drives hepatic IGF-1 expression. Studying them separately isolates the pathway; studying them together tests whether the inputs are additive or redundant — which is why paired reference sets are common here.

Half-life engineering

The practical difference between analogs in this category is usually duration rather than mechanism. A drug-affinity-complex conjugation extends plasma residence dramatically compared to the unmodified sequence, which changes pulse architecture rather than peak amplitude. Study designs that sample at a single timepoint will systematically misread that difference.

Endpoints to expect

GH pulse profiling with frequent sampling, IGF-1 quantification, and pituitary-cell culture assays for receptor-level response. Time-resolved sampling is non-negotiable in this category.

Common Questions

Growth & Performance — FAQ

Are these compounds sold for human use?
No. Every compound in this catalog is supplied strictly as a reference material for in-vitro laboratory research. They are not drugs, supplements, or cosmetics, and they are not for human or animal administration.
What purity standard applies?
Every batch is analyzed by reverse-phase HPLC at ≥98% purity, confirmed for identity by mass spectrometry, quantitatively assayed for content, and screened for heavy metals. Batch-specific third-party certificates are published on each product page.
Is bacteriostatic water included?
No. Diluent is supplied separately and is listed under Supplies. Bacteriostatic water (0.9% benzyl alcohol) is the standard laboratory diluent for multi-draw reference vials.
How should material be stored on arrival?
Lyophilized reference compounds are kept sealed and refrigerated at 2–8 °C for short-term working stock, or frozen at −20 °C or colder for long-term archive. Once reconstituted, solution is refrigerated, protected from light, and treated as a consumable.