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Research Use Only · Reference compounds for in-vitro laboratory study · Not for human or animal consumption

La Catégorie

Longevity & Cognitive

Reference compounds studied in preclinical models of mitochondrial function, telomerase activity, neurotrophic signaling, and cellular aging.

Reference Notes

Cellular energy and the aging phenotype

The longevity end of this category tracks a single connected system: NAD+ availability, sirtuin activity, and AMPK signaling together determine how a cell reads its own energy state and how aggressively it maintains its mitochondria. Cellular NAD+ declines across most aging models, and the sirtuins that depend on it as a cofactor slow with it. Compounds studied here are examined against oxygen-consumption rate, mitochondrial DNA copy number, and NAD+/NADH ratio.

The neurotrophic end

Cognitive-pathway research in this category is mechanism-level work on BDNF and NGF expression, Trk-receptor signaling, and neurite outgrowth in cultured neurons. The endpoints are molecular. Claims about cognition in an organism are a different category of evidence entirely and are not made here.

Why controls dominate this category

Aging endpoints drift slowly and noisily. Underpowered designs with two replicates produce publishable-looking curves that do not reproduce. Three independent biological replicates across separate passages is the practical floor.

Common Questions

Longevity & Cognitive — FAQ

Are these compounds sold for human use?
No. Every compound in this catalog is supplied strictly as a reference material for in-vitro laboratory research. They are not drugs, supplements, or cosmetics, and they are not for human or animal administration.
What purity standard applies?
Every batch is analyzed by reverse-phase HPLC at ≥98% purity, confirmed for identity by mass spectrometry, quantitatively assayed for content, and screened for heavy metals. Batch-specific third-party certificates are published on each product page.
Is bacteriostatic water included?
No. Diluent is supplied separately and is listed under Supplies. Bacteriostatic water (0.9% benzyl alcohol) is the standard laboratory diluent for multi-draw reference vials.
How should material be stored on arrival?
Lyophilized reference compounds are kept sealed and refrigerated at 2–8 °C for short-term working stock, or frozen at −20 °C or colder for long-term archive. Once reconstituted, solution is refrigerated, protected from light, and treated as a consumable.